Center for Outcomes Research in Liver Diseases | COR-LD

Our Purpose

The Center for Outcomes Research in Liver Diseases (COR-LD) has pioneered in outcomes research related to the areas of patient-reported outcomes (PROs), economic analysis, large database analysis, systematic reviews and meta-analysis involving different types of liver diseases. Additionally, COR-LD manages the Global NASH Council, the Global Liver Registry and the Global NASH Registry.

About Us

The Global NASH Council™

Non-alcoholic steatohepatitis (NASH) is increasingly recognized as one of the most common causes of liver disease worldwide. In order to understand the global impact of this disease, COR-LD has organized a Global Council of world renowned experts with interest in NASH to collaborate and exchange their views about NASH from different regions of the world. Global NASH Council include 35 countries from all the continents across the globe with 80 members. Members of the Council carry out multiple collaborative projects to better understand NASH, its clinical, economic and PRO burden.

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The Global NASH Registry™

Liver disease is among the most common causes of mortality and morbidity worldwide. Although the underlying etiology and causes of liver disease can vary according the region, NASH is rapidly becoming one of the most common causes of liver disease. The Global NASH Registry™ is developed to enroll subjects with NAFLD and NASH from different regions of the world. Additionally, patients with viral hepatitis B and C are enrolled as control subjects with other common liver diseases. Clinical data, laboratory data and PRO questionnaire data are obtained from each patient after informed consent. The de-identified data are entered through a centralized platform and patients are followed by each site on annual basis. This Global NASH Registry™ provides valuable real-world data about liver diseases across different regions. Currently, Global NASH Registry™ and Global Liver Registry™ includes 18 active sites with 15 additional upcoming sites.

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Our PRO Questionnaires

Members of COR-LD are leaders in developing and validating quality of life instruments, and performing PRO data analysis for patients with liver disease. Since mid-1990s, the team has developed and validated a number of disease-specific health-related quality of life instruments for liver disease such as Chronic Liver Disease Questionnaire (CLDQ) and its hepatitis C (CLDQ-HCV) and NASH (CLDQ-NASH) versions.

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Our Services

Quality of Life Questionnaires

Patient Reported Outcomes Data Analysis

Economic Analysis

Global NASH Council

Global Liver Registry